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Grants to USA, Canada, and International Developers for Vaccine Preparedness Research and Activities

Innovations to Prepare for Future Epidemics and Pandemics


Agency
Foundation

GrantWatch ID#
211655

Funding Source
CEPI
Array ( [0] => American Samoa (USA); [1] => Guam (USA); [2] => Puerto Rico (USA); [3] => Virgin Islands (USA); [4] => Northern Mariana Islands (USA); )

Geographic Focus
All USA
USA Territories: American Samoa (USA);   Guam (USA);   Puerto Rico (USA);   Virgin Islands (USA);   Northern Mariana Islands (USA);
USA Compact Free Associations:The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)
International, Israel and Canada.

Important Dates
Deadline: 02/12/24 23.59 CET - For Focus Area 3; Proposals for Focus Areas 1 and 2 are accepted on a rolling basis through 2026. Save

Grant Description
Grants to USA, Canada, and International developers for vaccine preparedness research and activities. Applicants are required to contact the funding source to gain access to the application portal. Funding is intended to develop vaccine mechanisms for identified and as yet unidentified epidemic and pandemic threats. Developers based in the Global South are particularly encouraged to apply.

CEPI’s Innovations to Prepare for Future Epidemics and Pandemics Call for Proposals aims to support CEPI’s mission by advancing a broad range of vaccine innovations for pathogens with epidemic or pandemic potential, including novel pathogens capable of infecting and causing disease in humans (i.e., Disease X).

It will support vaccine research, development and manufacturing innovations for CEPI’s priority pathogens and contribute towards the 100 Days Mission, thereby helping the world prepare for known and future epidemic and pandemic threats.

Through the Innovations to Prepare for Future Epidemics and Pandemics Call for Proposals CEPI will advance cutting-edge vaccine development and manufacturing science and technologies that will contribute to speed, scale and equitable access during future outbreak response. It initially invites applications across three Focus Areas:

  • Focus Area 1: advancing innovative rapid-response vaccine platforms that can transform the response to a future Disease X.
    • Objectives: The objective of Focus Area 1 is to advance vaccine platforms that can transform outbreak response to Disease X, addressing needs for speed, safety/efficacy, and access. Through proposals awarded under this Focus Area, CEPI aims to build significant preclinical, CMC, clinical, and regulatory expertise with vaccine platforms that could be leveraged for rapid adoption in an outbreak and made accessible to all populations that need them.
  • Focus Area 2: developing new vaccine candidates against CEPI priority pathogens with epidemic or pandemic potential and viral families.
    • Objectives: The objective for Focus Area 2 is to advance new candidates for CEPI priority pathogens and viral families, aligned with CEPI’s strategic objectives to accelerate development of vaccines against known high-risk pathogens and to build a library of vaccine prototypes from high-risk viral families to give a head-start on novel threats (Disease X).
  • Focus Area 3: advancing manufacturing innovations that improve vaccine scalability and equitable access.
    • Objectives: This Focus Area aims to advance technologies and innovations that contribute to the goals of:
      • Manufacturing at commercial scale within 100 days of recognition of a pandemic pathogen.
      • Equitable access especially in the Global South, by significantly lowering the cost of goods of vaccines, and by facilitating distribution and delivery.

For additional information regarding these focus areas, see the individual guidelines, in Supporting Documents, below. 



Recipient

Additional Eligibility Criteria
Vaccine developers worldwide are eligible to apply.
- Developers based in the Global South are particularly encouraged to apply.

Focus Area 1:
- Developers with very early-stage technologies can apply for an Exploratory Award.

Focus Area 2:
While CEPI is open to candidates from applicants/developers globally, preference will be given to proposals from groups based in RVF-endemic regions (i.e., Africa and the Middle East), or with plans to conduct clinical evaluation of candidates in endemic areas. CEPI is particularly interested in candidates that utilize RNA- (any modality), viral-vector-, or protein-based vaccine platforms.

Ineligible
Focus Area 2:
- Rift Valley Fever: Live attenuated RVF vaccine candidates, regardless of generation or development stage, are out of scope.
- Pan-Sarbecovirus or other coronaviruses: Development of SARS-CoV-2 seasonal variant vaccines/boosters is out of scope.

For information regarding activities out of scope for Focus Area 3, see: https://cepi.net/wp-content/uploads/2023/10/Innovations-to-Prepare-for-Future-Epidemics-and-Pandemics_FA3_CfP-Oct2023.pdf#page=3

Pre-Application Information
CEPI welcomes proposals for Focus Areas 1 and 2 on a rolling basis through 2026.
Applications will be accepted beginning on 24 October 2023, with application deadlines at 23:59 CET on December 14, 2026.

Proposals for Focus Area 3 can be submitted through 12 February 2024 at 23.59 CET. Call deadlines may be subject to amendment.

Prior to submitting an application, CEPI strongly encourages you to contact the team to discuss your product, technology, or innovation and confirm your proposed project is aligned with the current needs and priorities of one or more Focus Areas.

Applicants should inform CEPI of their intent to apply as soon as possible by email, below. In the subject line of the email, applicants should note the Focus Area under which they intend to apply. Applicants intending to apply will receive instructions for uploading their completed template via CEPI’s secure online portal.

All communication of information and application documents must be in English.

All budget amounts must be submitted in US dollars.

Estimated Size of Grant
Focus Area 1:
- Exploratory Award of up to US $1M
- All other applications under Focus Area 1 (i.e., for platform development) may seek initial funding of up to US $5M

Focus Area 3:
Budget not to exceed $5,000,000 USD

Term of Contract
Focus Area 1:
- Exploratory Award - 18 months
- All other applications under Focus Area 1 may seek funding for a maximum of 36 months.

Focus Area 2:
The timeline for proposed studies must not exceed 5 years.

Focus Area 3: Timeline may not exceed 36 months.

Contact Information
Contact the team at innovations.cfp@cepi.net

CEPI
1901 Pennsylvania Ave, NW; Suite 1003
Washington, DC 20006

Gibbs Building, 215 Euston Rd
Bloomsbury, London
NW1 2BE, UK

Skøyen Atrium, Askekroken 11
0277 Oslo

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